
Oxazole
Oxazole is produced as a co-product in INEOS process for manufacturing acrylonitrile by ammoxidation of propylene. It is not an easily synthesized molecule and has been unavailable in large quantities because of high synthesis costs. We have developed proprietary technology for extracting and purifying oxazole with a typical purity greater than 98 percent. Our novel process makes oxazole now commercially available at a reasonable cost.
Recent activity in the patent literature indicates that molecules incorporating the oxazole ring are finding increasing utility. For example, oxazole has been reported to be useful as an oil additive and as a solvent in several industrial applications. Additionally, patent activity in oxazole derivatives in the pharmaceutical industry has been especially noteworthy. Several candidate non-steroidal anti-inflammatory drugs and antimicrobial medications are in various stages of development. The commercial availability of oxazole will make synthetic routes to these more complex molecules increasingly attractive.
Recently INEOS entered into a cooperative agreement with Cambridge Major Laboratories, an outsourcing partner to the world's leading pharmaceutical and biotechnology companies, for the development and marketing of oxazole derivatives.
Ammonium Sulphate
Ammonium Sulphate is a co-product in the INEOS process for manufacturing acrylontrile by ammoxidation of propylene. Ammonium Sulphate slurry is formed from the neutralization of ammonia with sulphuric acid and is then recovered via a centrifugal separation and dried . INEOS Köln ( Germany) plant recovers Ammonium Sulphate to standard market specifications and sell the product in crystalline form.
Ammonium Sulphate is used in various industrial areas but its key application is the fertilizer industry where it is used as one of the building blocks of fertilizers. It is largely used as an artificial fertilizer for alkaline soils. The sulphate ion is released in the soil and forms sulphuric acid, lowering the PH balance of the soil, while contributing essential nitrogen for plant growth.